Two mysterious women seek refuge in a run-down coastal resort. Clara (Gemma Arterton - Prince of Persia: The Sands of Time, Clash of the Titans) meets lonely Noel, who provides shelter in his deserted guesthouse, Byzantium. Schoolgirl Eleanor (Saoirse Ronan - Hanna, The Lovely Bones, Atonement) befriends Frank and tells him their lethal secret. They were born 200 years ago and survive on human blood. As knowledge of their secret spreads, their past catches up on them with deathly consequence.