My Life in the Bush of Ghosts is a 1981 album by Brian Eno and David Byrne, titled after Amos Tutuola's 1954 novel of the same name. The album was re-released in expanded form in 2006.

Receiving strong reviews upon its release, My Life is now regarded as a high point in the discographies of Eno and Byrne. In a 1985 interview, singer Kate Bush remarked that the album "left a very big mark on popular music," while critic John Bush describes it as a "pioneering work for countless styles connected to electronics, ambience, and Third World music." The extensive use of sampling on My Life is widely considered ground-breaking—it was one of the first albums to do so—but its actual influence on the sample-based music genres that later emerged continues to be debated.

Pitchfork Media listed My Life in the Bush of Ghosts as 21st best album of the 1980s. Slant Magazine listed the album at #83 on its list of "Best Albums of the 1980's".

Eno and Byrne first worked together while collaborating on More Songs About Buildings and Food, the 1978 album by Byrne's band Talking Heads.