Britt Reid (Seth Rogen) verbringt die Tage als Faulenzer und die Nächte als Partylöwe... bis er eine echt seriöse, echt coole Karriere als Verbrechen bekämpfender Actionheld startet. Als The Green Hornet schließt er sich mit dem genialen Tüftler und Kampfsportmeister Kato (Jay Chou) zusammen, um die Unterwelt von LA aufzumischen. Nicht mal Britts Assistentin Lenore (Cameron Diaz) vermutet hinter dem ungleichen Paar das maskierte Duo, das die schlimmsten Verbrecher der Stadt, samt ihrem Anführer Chudnofsky (Oscar(r)-Preisträger Christoph Waltz), hochgehen lässt. Mit Stil, Überheblichkeit und einem ganzen Arsenal an fantastischer Ausrüstung sorgen The Green Hornet und Kato auf ihre Weise für Gerechtigkeit, was aus jeder ihrer Missionen eine Mischung aus überzogener Action und haarsträubender Comedy macht.
| Seth Rogen | Britt Reid |
| Cameron Diaz | Lenore Case |
| Christoph Waltz | Chudnofsky |
| Edward Furlong | Tupper |
| Edward James Olmos | Mike Axford |
| Jay Chou | Kato |
| Tom Wilkinson | James Reid |
| David Harbour | D.A. Frank Scanlon |
| Jamie Harris | Popeye |
| Chad L. Coleman | |
| Chad Coleman | Chili |
| Jill Remez | Daily Sentinel Reporter |
| Joe O'Connor | Daily Sentinel Reporter |
| Morgan Rusler | Daily Sentinel Reporter |
| Joshua Erenberg | Young Britt |
| Analeigh Tipton | Ana Lee |
| Taylor Cole | Limo Girl |
| Robert Clotworthy | Politician |
| Jamison Yang | City Hall Reporter |
| Michael Holden | Funeral Businessman |
| Irene White | Maid |
| Gary Davis | Police Officer |
| Billy Mayo | Police Officer |
| Brandon Rudat | TV Anchor |
| Beverly Brooks | TV Anchor |
| Lu Parker | TV Anchor |
| Diane Mizota | TV Reporter (Reid Estate) |
| Theodore Bressman | Daniel Vertlieb / Dead Reporter |
| Dave Rickley | Archive Reporter |
| Dina Mamedova | Russian Aftermath Reporter |
| Tanner Gill | SWAT Leader |
| George Fisher | Chauffeur |
| Daniel Arrias | Drug Dealer |
| Eddie Perez | Drug Dealer |
| Bryan Thompson | Crackhead |
| Reuben Langdon | Crackhead |
| Ameer Alexander | Armenian Gang Boss |
| Alexandra Lord | Pool Girl |
| Christy Petersen | Pool Girl |
| Frederick C. Ruiz | Club Bouncer |
| Keith Adams | Chudnofsky's Gang |
| Dennis Keiffer | Chudnofsky's Gang |
| Travon Magee | Chudnofsky's Gang |
| David Powledge | Chudnofsky's Gang |
| Jerry Trimble | Chudnofsky's Gang |
| Bart Baggett | Nerdy Guy (uncredited) |
| Joel Clark Ackerman | Music Reporter |
| Austin Michael Coleman | Playground Bully (uncredited) |
| Zoli Dora | Printing Press Gang (uncredited) |
| Mike Foxx | Reporter (uncredited) |
| James Franco | Danny Crystal Cleer |
| Giovanni V. Giusti | Drug Dealer (uncredited) |
| Larry Goldstein | Daily Sentinel Reporter |
| Thayr Harris | Mohawk Crackhead (uncredited) |
| Kiralee Hayashi | Couple Gal (uncredited) |
| Don Kress | Chudnofsky's Gang |
| Maximilian Law | Thug (uncredited) |
| Jean Claude Leuyer | SWAT (uncredited) |
| Hunter James Mckeever | Private School Boy (uncredited) |
| Ashlyn Miyasaki | Masseuse A (uncredited) |
| Les Mumphrey | Hipster (uncredited) |
| Deborah Rombaut | Heavy Metal Groupie (uncredited) |
| Brandon Rush | TV Anchor |
| Sarah Skeeters | Reporter (uncredited) |
| Kurt E. Soderling | Helicopter Co-Pilot (uncredited) |
| Michael A. Templeton | Man Unveiling Statue (uncredited) |
